On August 12, 2025, a multi-vehicle crash on Interstate 40 Westbound in Roane County, Tennessee, at Mile Marker 351, reported at 12:13 PM CDT, led to the complete closure of the westbound lanes, causing significant traffic disruptions.

The incident triggered congestion in both directions of the interstate, with eastbound congestion reported at Mile Marker 348 and westbound congestion at Mile Marker 356, though no lanes were blocked in these areas.

To manage the traffic flow, a diversion route was established at Exit 352 onto SR-58 South toward Kingston with no lanes blocked on the westbound side at that point. These events, combined with the ongoing flood advisory in nearby Anderson and Knox counties due to heavy rainfall, have exacerbated travel challenges in the region, particularly for motorists navigating low-lying or poorly drained areas.