Police in the northern Spanish city of Barcelona say a white van has jumped the sidewalk in the city’s historic Las Ramblas district, killing at least 13 people and injuring more than 80. Spanish public broadcaster RTVE says two suspects have been arrested.

Police are treating the incident as a terror attack.

“We confirm the terrorist attack,” Catalan police said. “The protocol for terrorist attacks has been activated.”

A regional interior minister confirmed on Twitter that at least 13 people were killed in the attack and more than 80 injured.

In a photograph shown by RTVE, at least five people were lying on the ground in the street Thursday afternoon and were apparently being helped by police and others. Videos of the scene recorded people screaming as they fled.

At this time, the extent of the victims’ injuries remains unclear.

On Twitter, Spanish Prime Minister Mariano Rajoy said he is in contact with authorities and the priority is to attend to the injured.

Reuters reports two armed men reportedly entered a restaurant following the crash. Police say they have located a second van connected to the attack in the town of Vic.

Spain’s El Pais newspaper, citing police sources, says perpetrators of the van incident are holed up in a bar. Armed police ran down the streets and through a market, checking in stores and cafes, presumably in search of them.